PIK3CA p.H1047R Reference Standard
- CBP10319
- Cobioer
- 上海市
- 现货
- 1ug
- 900 元
- 2022-09-15 15:47:19
南京科佰生物科技有限公司
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CBP10319
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| Format | Genomic DNA |
| Description | PIK3CA H1047R is a hotspot mutation that lies within the kinase domain of the Pik3ca protein (UniProt.org). H1047R confers a gain of function on the Pik3ca protein as indicated by increased phosphorylation of Akt and Mek1/2, growth factor-independent cell survival, and transformation in cell culture (PMID: 26627007, PMID: 29533785). |
| Technical Data | |
| DNA Change | c.3140A>G |
| AA Change | p.H1047R |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | NM_006218.1 |
| Cosmic ID | COSM775 |
| Chr position(GRCh37) | chr3:178952085 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |   |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
