Anti RhoA Mouse Monoclonal Antibody
- CR-M26007
- 科博瑞生物
- 湖北省武汉市
- 现货
- 100ul
- 2800 元
- 2024-05-30 14:35:54
科博瑞（武汉）生物科技有限公司
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- 种属
- Mouse
RhoA [CR-M26007]
[100 µL]
| Catalog Number: CR-M26007 |
| Gene Symbol: RHOA |
| Description: Anti RhoA Mouse Monoclonal Antibody |
| Background: Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell motility, contraction, and cytokinesis. It regulates the formation of stress fibers and focal adhesions in fibroblasts and Ca2+ sensitivity of smooth muscle contraction. |
| Immunogen: : Recombinant full length protein of RhoA. |
| Applications: ELISA, WB, IHC |
| Recommended Dilutions: ELISA 1:1000-1:5000 WB 1:1000-1:2000 |
| Concentration: 1 mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: : PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: RhoA antibody recognizes RhoA from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Western Blot: |
 |
Western blot analysis of RhoA proteins. MEF whole-cell lysate was used for western blot with the anti-RhoA mouse monoclonal antibody (Cat. # CR-M26008). |
| Publications: |
| 1. Ethanol increases p190RhoGAP activity, leading to actin cytoskeleton rearrangements J Neurochem. 2011 Dec;119(6):1306-16 |
| 2. The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1 Oncogene. 2012 Aug 30;31(35):3913-23 |
| 3. G(alpha)12/13 inhibition enhances the anticancer effect of bortezomib through PSMB5 downregulation Carcinogenesis. 2010 Jul;31(7):1230-7 |
| 4. Transgenesis of the Wolffian duct visualizes dynamic behavior of cells undergoing tubulogenesis in vivo Development, Growth & Differentiation. Volume 55, Issue 4, pages 579–590, May 2013 |
| 5. Foxc2 induces Wnt4 and Bmp4 expression during muscle regeneration and osteogenesis Cell Death and Differentiation (2013) 20, 1031–1042 |
| 6. N-glycosylation induces collagen triple helix repeat containing 1 (CTHRC1) and drives oral cancer cell migration J Biol Chem. 2013 Jul 12;288(28):20217-27 |
| 7. Cyclodextrin protects podocytes in diabetic kidney disease Diabetes. 2013 Nov;62(11):3817-27 |
| 8. Amyloid beta1-42 (Aβ42) up-regulates the expression of sortilin via the p75NTR/RhoA signaling pathway Journal of Neurochemistry Volume 127, Issue 2, pages 152–162, October 2013 |
| 9. Podocyte-specific GLUT4 deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy Diabetes. 2014 Feb;63(2):701-14 |
| 10. Loss of TAK1 increases cell traction force in a ROS-dependent manner to drive epithelial–mesenchymal transition of cancer cells Cell Death and Disease (2013) 4, e848 |
| 11. Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases Biochimica et Biophysica Acta (BBA) - General Subjects Volume 1840, Issue 8, August 2014, Pages 2482–2490 |
| 12. Epithelial repair is a two-stage process driven first by dying cells and then by their neighbours J Cell Sci. 2014 Mar 15;127(Pt 6):1229-41 |
| 13. MIF inhibits monocytic movement through a non-canonical receptor and disruption of temporal Rho GTPase activities in U-937 cells Cytokine Volume 69, Issue 1, September 2014, Pages 47–55 |
| 14. Triclosan Potentiates Epithelial-To-Mesenchymal Transition in Anoikis-Resistant Human Lung Cancer Cells PLoS One. 2014 Oct 16;9(10):e110851 |
