Recombinant SARS-CoV-2 Envelope Protein is produced by our E.coli expression system and the target gene encoding Met1-Val75 is expressed with a BBP, 6His tag at the N-terminus.

2019-nCoV E protein; 2019-nCoV sM protein

27.5kDa

22-25kDa, reducing conditions

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, pH 8.0

Reconstituted protein solution should be stored at ≤ -20°C.
Stable for at least 24 months when stored as instructed.

The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.

Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.