Anti Active Rab11 Mouse Monoclonal Antibody
- CR-M26919
- 科博瑞生物
- 湖北省武汉市
- 现货
- 30ul
- 4800 元
- 2024-06-12 15:44:13
科博瑞（武汉）生物科技有限公司
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- 种属
- Mouse
Active Rab11 GTP [CR-M26919]
[30 µL]
| Catalog Number: CR-M26919 |
| Gene Symbol: RAB11 |
|
Description: Anti Active Rab11 Mouse Monoclonal Antibody
|
| Background: Small GTPases of the Rab-family are crucial elements of the machinery that controls membrane traffic. Rab11 has been shown to control traffic through the recycling endosome. |
| Immunogen: Recombinant full length protein of active Rab11 |
| Applications: IP, IHC |
| Recommended Dilutions: IP: 1 μg for 1~2 mg total cellular proteins IHC: 1:50~100 dilution |
| Concentration: 1 mg/ml |
| Host: mouse |
| Format: Liquid |
| Clonality: Monoclonal |
| Isotype: IgG2b |
| Purity: Purified from ascites |
| Storage buffer: |
| Preservative: no |
| Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
| Species Reactivity: Anti-active Rab11 antibody recognizes active Rab11 from vertebrates. |
| Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
| Immunoprecipitation/Western blot: |
 |
Purified full-length Rab11 proteins were immunoprecipitated after treated with GDP (lane left) or GTPγS (lane right). Immunoprecipitation was done with the anti-active Rab11 monoclonal antibody (Cat. No. CR-M26919). Immunoblot was with an anti-Rab5 polyclonal antibody (Cat. No. CR-M21157). |
| Publications: |
| 1. VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors Hepatology Volume 61, Issue 1, pages 361–374, January 2015 |
| 2. Rab5 Activity Regulates GLUT4 Sorting into Insulin-Responsive and Non-Insulin-Responsive Endosomal Compartments: A Potential Mechanism for Development of Insulin Resistance Endocrinology. 2014 Sep;155(9):3315-28 |
