Adalimumab
- HY-P9908
- 皓元医药
- 上海市
- 一周内
- 5mg
- 5700 元
- 2022-07-23 11:37:26
上海皓元生物医药科技有限公司
- CAS号
- 331731-18-1
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Adalimumab
产品活性:Adalimumab 是一种人源的单克隆 IgG1 抗体,靶向肿瘤坏死因子α (TNF-α)。
研究领域:Apoptosis
作用靶点:TNF Receptor
In Vitro: Treatment of HUVECs with Adalimumab for up to 12 hours shows no adverse effect on their cell viability, even with a 10-fold higher concentration of Adalimumab than used in this study.
In Vivo: The elimination half-life (t1/2) of Adalimumab is long (~20 days). The enriched fluorescent-labelled adalimumab is observed mainly in major Oil red O-positive lesions documenting good tissue penetration of the drug into the atherosclerotic plaque, without background fluorescence of the vessel wall after vehicle control injection into hypercholesterolemic Ldlr-/- mice.
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