肺Kruppel样因子抗体
KLF2 Rabbit pAb
- bs-2772R
- 北京博奥森
- 北京市
- 现货
- 按需
- 议价
- 2023-10-18 12:01:15
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- 英文名称
- KLF2 Rabbit pAb
- 别名
- Kruppel like factor 2; Kruppel like factor; Kruppel like factor LKLF; Kruppel-like factor 2 (lung); Lung krueppel like factor; Lung Kruppel like zinc finger transcription factor; KLF 2; Klf2; KLF2_HUMAN; Krueppel-like factor 2; Lklf; Lung krueppel like factor; Lung krueppel-like factor; Lung Kruppel like zinc finger transcription factor.
产品编号
bs-2772R
产品分类
一抗
产品类型
质检1级
英文名称
KLF2 Rabbit pAb
中文名称
肺Kruppel样因子抗体
英文别名
Kruppel like factor 2; Kruppel like factor; Kruppel like factor LKLF; Kruppel-like factor 2 (lung); Lung krueppel like factor; Lung Kruppel like zinc finger transcription factor; KLF 2; Klf2; KLF2_HUMAN; Krueppel-like factor 2; Lklf; Lung krueppel like factor; Lung krueppel-like factor; Lung Kruppel like zinc finger transcription factor.
交叉反应
Human,Mouse,Rat（predicted：Pig,Cow,Horse,Rabbit,Sheep）
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human KLF2
亚型
IgG
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
37kDa
浓度
1mg/ml
储存液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
功能
Binds to the CACCC box in the beta-globin gene promoter and activates transcription .
亚基
Interacts with WWP1.
亚细胞定位
Nucleus.
翻译后修饰
Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein.
相似性
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 3 C2H2-type zinc fingers.
Contains 3 C2H2-type zinc fingers.
数据库链接
Entrez Gene: 10365 Human
Entrez Gene: 16598 Mouse
Omim: 602016 Human
SwissProt: Q9Y5W3 Human
SwissProt: Q60843 Mouse
Unigene: 107740 Human
Unigene: 726356 Human
Unigene: 26938 Mouse
Unigene: 92653 Rat
背景资料
Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011]
