葡聚糖硫酸钠, 分子量8, 000
- 02101516-CF
- 安倍医疗
- 上海市
- 现货
- 1 x 1g
- 1 x 10g
- 1 x 50g
- 1 x 100g
- 2022-12-17 15:27:21
安倍医疗器械贸易（上海）有限公司
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- CAS号
- 9011-18-1
SYNONYMS Dextran sodium sulfate; DSS
CAS NUMBER:9011-18-1
MOLECULAR WEIGHT:8000 (avg) Da
MDL NUMBER:MFCD00081551
PACKAGING OPTIONS1 x 1 g 1 x 10 g 1 x 50 g 1 x 100 g
Product Description
Dextran Sulfate Sodium Salt (8,000 (avg) Da M.Wt)
Application Notes
Dextran Sulfate Sodium (DSS) which has proven to have versatile value in Biomedical/clinical research. DSS can be used as an anticoagulant, antiviral as well as antilipemic agent.Dextran sulfate sodium shows immunologically relevant activities: enhancement and suppression of humoral immunity, polyclonal activation of B-lymphocytes, stimulating even immature B cells, changes in thymocyte reactivity to lectins, enhancement/suppression of cell-mediated immune responses. Precipitates LDL and VLDL lipoproteins - in the presence of magnesium ions, dextran sulfate precipitates low-density lipoproteins from human serum leaving the high-density lipoproteins in the supernatant. Removal of lipoproteins by dextran sulfate precipitation may be useful in the purification of other materials such as beta 2 glycoprotein. Exhibits activity as an adjuvant.Antiviral and Antienzyme Activity – Baba et al., have shown in In Vitro studies that DSS inhibits the binding of various enveloped viruses including Human Immunodeficiency Virus (HIV), Herpes Virus (HSV) and Cytomegalovirus (CMV) to cells. Additionally, DSS has also shown to exhibit a potent inhibitory effect on many enzymes, for example hyaluronidase, adenylate cyclase, and amylase. Hofer at al., have shown that DSS induces bacterial translocation in HIV-infected humanized mice.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Immunology | Antiviral | Antilipemic | Anticoagulant
Specifications
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SKU
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02101516-CF
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Alternate Names
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Dextran sodium sulfate; DSS
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Application Notes
|
Dextran Sulfate Sodium (DSS) which has proven to have versatile value in Biomedical/clinical research. DSS can be used as an anticoagulant, antiviral as well as antilipemic agent.Dextran sulfate sodium shows immunologically relevant activities: enhancement and suppression of humoral immunity, polyclonal activation of B-lymphocytes, stimulating even immature B cells, changes in thymocyte reactivity to lectins, enhancement/suppression of cell-mediated immune responses. Precipitates LDL and VLDL lipoproteins - in the presence of magnesium ions, dextran sulfate precipitates low-density lipoproteins from human serum leaving the high-density lipoproteins in the supernatant. Removal of lipoproteins by dextran sulfate precipitation may be useful in the purification of other materials such as beta 2 glycoprotein. Exhibits activity as an adjuvant.Antiviral and Antienzyme Activity – Baba et al., have shown in In Vitro studies that DSS inhibits the binding of various enveloped viruses including Human Immunodeficiency Virus (HIV), Herpes Virus (HSV) and Cytomegalovirus (CMV) to cells. Additionally, DSS has also shown to exhibit a potent inhibitory effect on many enzymes, for example hyaluronidase, adenylate cyclase, and amylase. Hofer at al., have shown that DSS induces bacterial translocation in HIV-infected humanized mice.
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Base Catalog Number
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101516
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Boiling Point
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310 °C
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CAS #
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9011-18-1
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Grade
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Reagent Grade
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Melting Point
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92 °C
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Molecular Weight
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8000 (avg) Da
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Optical Rotation
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+75 ° to 105 °
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Personal Protective Equipment
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Eyeshields, Gloves, respirator filter
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RTECS Number
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HH9290000
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Solubility
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>24.8 [ug/mL]
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Usage Statement
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Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
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|
Vapor Pressure
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2.6X10-4 mm Hg at 25 deg C /Estimated/
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