血管活性肠肽封闭多肽
VIP Antibody Blocking Peptide
- bs-0077P
- 北京博奥森
- 北京市
- 现货
- 500ug
- 议价
- 2023-10-09 09:26:14
北京博奥森生物技术有限公司
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- 英文名称
- VIP Antibody Blocking Peptide
产品编号
bs-0077P
产品分类
合成多肽
英文名称
VIP Antibody Blocking Peptide
中文名称
血管活性肠肽封闭多肽
英文别名
Vasoactive Intestinal peptide; MGC13587; Peptide histidine methioninamide 27; PHM 27; PHM27; PHV42; VIP peptides precursor; PHI; Peptide Histidine Isoleucine; Vasoactive intestinal peptide; VIP_HUMAN.
蛋白细胞定位
分泌型蛋白
纯化方法
HPLC
GeneID
7432
Swiss
P01282
保存条件
Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Subunit
Subcellular Location
Secreted.
Similarity
Belongs to the glucagon family.
Database links
Entrez Gene: 7432 Human
Entrez Gene: 22353 Mouse
Omim: 192320 Human
SwissProt: P01282 Human
SwissProt: P32648 Mouse
Unigene: 53973 Human
Unigene: 98916 Mouse
Unigene: 18675 Rat
背景资料
Growth Factor and Hormones
VIP(Vasoactive Intestinal peptide) is a 28-amino acid peptide structurally related tosecretin. It was originally isolated from intestinal extracts and shown to be a potent vasodilator. Subsequent work demonstrated that VIP is very widely distributed in the peripheral and central nervous systems, and probably should not be considered a true GI hormone. A huge number of biological effects have been attributed to VIP. With respect to the digestive system, VIP seems to induce smooth muscle relaxation (lower esophageal sphincter, stomach, gallbladder), stimulate secretion of water into pancreatic juice and bile, and cause inhibition of gastric acid secretion and absorption from the intestinal lumen.
VIP(Vasoactive Intestinal peptide) is a 28-amino acid peptide structurally related tosecretin. It was originally isolated from intestinal extracts and shown to be a potent vasodilator. Subsequent work demonstrated that VIP is very widely distributed in the peripheral and central nervous systems, and probably should not be considered a true GI hormone. A huge number of biological effects have been attributed to VIP. With respect to the digestive system, VIP seems to induce smooth muscle relaxation (lower esophageal sphincter, stomach, gallbladder), stimulate secretion of water into pancreatic juice and bile, and cause inhibition of gastric acid secretion and absorption from the intestinal lumen.
VIP是一个广泛分布于中枢神经系统和周围神经系统的神经肽，他有较强的血管舒张作用、支气管扩张作用、平滑肌松弛作用，具有很多免疫系统细胞的活性，是一个促分裂剂。
近年来研究表明，VIP也是一种生长因子,它对多种恶性肿瘤的发生、发展、增殖和分化起重要的促进作用，血管活性肠肽的神经保护作用受到来自胶质细胞的活性依赖的神经营养因子释放的调节。VIP和PACAP有很高的同源性。
近年来研究表明，VIP也是一种生长因子,它对多种恶性肿瘤的发生、发展、增殖和分化起重要的促进作用，血管活性肠肽的神经保护作用受到来自胶质细胞的活性依赖的神经营养因子释放的调节。VIP和PACAP有很高的同源性。
多肽活性
Yes
