Catalog Number	PME100533
Package	10 μg ￥600.00 ; 50 μg ￥2350.00 ; 100 μg ￥3380.00
Description	Recombinant Human AXL with C-terminal mouse Fc
Synonyms	AXL,UFO
Uniprot ID
Expression Host	HEK293
Tag	C-Mouse Fc tag
Molecular Characterization
Molecular Weight	The protein has a predicted molecular mass of 72.0 kDa after removal of the signal peptide.The apparent molecular mass of AXL-mFc is approximately 100-130 kDa due to glycosylation.
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Storage	Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage	Research use only
Images	Figure 1. Human AXL Protein, mFc Tag on SDS-PAGE under reducing condition.
Background	The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.

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