发布需求
请登录 注册
C02601 轮状病毒单抗 Rotavirus-mAb (Mouse,包被抗体)
  • C02601
  • 东抗生物
  • 江苏省南通市
  • 现货
  • 按需定制
  • 议价
  • 2022-10-21 09:58:58

江苏东抗生物医药科技有限公司

一键申请试用
咨询
加入意向单
联系方式

 

Description:

Rotavirus, member of Reoviridae family, is a non-enveloped double-stranded RNA (dsRNA) virus whose architecture is that three concentric capsids surround a genome of 11 segments of dsRNA. The RNA encodes six structural proteins (VP1, VP2, VP3, VP4, VP6 and VP7) and six non-structural proteins (NSP1, NSP2, NSP3, NSP4, NSP5 and NSP6), both determining the host specificity, cell entry and enzymatic functions and comprising epitopes that generate immune responses. The non-structural proteins are associated with genome replication. Two rotavirus vaccines are broadly used worldwide: the RV5 vaccine and the RV1 vaccine. RV5 vaccine is a live attenuated pentavalent vaccine,while the RV1 vaccine is a live attenuated human monovalent virus vaccine.

 

 

 

图1 轮状病毒结构示意图

 

 

 

 

图2 轮状病毒复制周期

 

 

 

 

 

 

 

 

 

 

 

参考文献:

[1] Crawford SE, et al. 2017. Nat Rev Dis Primers. 3:17083.

[2] Mahmud-Al-Rafat A, et al. 2018. Infection. 46(1):15-24.

发布需求

意向单

反馈

400-661-8020

扫码关注订阅号
返回顶部